Data were analysed using logistic regression and by calculating relative risks (RR). Subsequently, we recruited a further 622 patients between 2016-2017. In a prospective cohort study in Callao, Peru, we recruited and interviewed 2,584 patients with tuberculosis between 2007-2013 and followed them until 2016 for adverse treatment outcomes using national treatment registers. We studied mobile phone access amongst patients with tuberculosis, focusing on vulnerable patients and patients who later had adverse treatment outcomes. Mobile phone interventions have been advocated for tuberculosis care, but little is known about access of target populations to mobile phones. Saunders, Matthew J Wingfield, Tom Tovar, Marco A Herlihy, Niamh Rocha, Claudio Zevallos, Karine Montoya, Rosario Ramos, Eric Datta, Sumona Evans, Carlton A Mobile phone interventions for tuberculosis should ensure access to mobile phones to enhance equity - A prospective, observational cohort study in Peruvian shantytowns. The app is designed to lower the barriers to accessing this information, so that all researchers with an interest in combatting this deadly disease can use it freely to the benefit of their own efforts. Conclusions TB Mobile may assist researchers as part of their workflow in identifying potential targets for hits generated from phenotypic screening and in prioritizing them for further follow-up. By input of a molecular structures and performing a similarity search within the app we can infer potential targets or search by targets to retrieve compounds known to be active. Therefore we have used this set of over 700 molecules screened versus Mtb and their targets to create a free mobile app (TB Mobile) that displays molecule structures and links to the bioinformatics data.
The development of mobile cheminformatics apps could lower the barrier to drug discovery and promote collaboration. This dataset contains published data on target, essentiality, links to PubMed, TBDB, TBCyc (which provides a pathway-based visualization of the entire cellular biochemical network) and human homolog information. Results In order to learn from prior work we have collated information on molecules screened versus Mtb and their targets which has been made available in the Collaborative Drug Discovery (CDD) database. TB Mobile: a mobile app for anti- tuberculosis molecules with known targetsīackground An increasing number of researchers are focused on strategies for developing inhibitors of Mycobacterium tuberculosis (Mtb) as tuberculosis (TB) drugs.
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